Scientists have found a way to double the muscle mass without exercise

Scientists at the Salk Institute for Biological Research (USA) have found a way, acting on the genes, to achieve a twofold increase in muscle strength and endurance.
The researchers conducted experiments on mice and worms and are confident that in the same way, this technology will work on other animals up to man.
It is known that the growth of any tissue and any body at a certain moment hampered by special proteins that bind to genes and the development of inactivated. It is a necessity, if allowed to grow unchecked tissue, the result is easy to get cancer. The above proteins are constantly sitting on the respective genes, not allowing them to wake up. Protein NCoR1 monitors, in particular, the genes that control development of muscle tissue. The idea of ​​the researchers was to suppress the work of the most of this protein. Mice in which this is done by demonstrating greater strength and endurance, running twice as fast, and longer than normal animals, and in addition, were more resistant to cold, according to compulenta. ru.
Without inhibitor NCoR1 animals fastened muscle mass, and muscle cells increased the number and activity of mitochondria, which supply cells with energy. Exactly the same effect, researchers have observed and nematode worms that have switched off their analogue NCoR1. According to scientists, this protein can be made to enable subordinate genes, if you put the cage with the need to burn fat. In this case, the activation of oxidative metabolism, and maintenance NCoR1 to DNA is only one step in reconfiguring the metabolism.
The peculiarity of the research is that scientists have not been working on ways to activate genes that control muscle development, and approached the problem from another side by acting on the molecular genetic brake this process.
To turn off NCoR1, the authors carried out a very complicated genetic engineering manipulations, however, said they did not take much to create a drug that can inhibit the work NCoR1 without any interference in human genetics.